The expansion Montreal Expos, in their first game, faced the New York Mets.
"Mudcat Grant started for the Expos, and Tom Seaver started for the New York Mets," Van Horne said. "It was my first big league game."
Also of note, it was the first Major League Baseball game involving a team located outside of the United States. It was the first time the national anthems of Canada and the United States were played before an MLB game.
The Expos won, 11-10.
"The Mets, however, went on to have their miracle year, and won the World Series championship," Van Horne said.
Monday marks another beginning for Van Horne. The veteran broadcaster also is embarking on his 12th season as the radio voice of the Marlins.
Van Horne, the Ford C. Frick Award winner in 2011, and Glenn Geffner once again will be broadcasting the Marlins on flagship station, 790 The Ticket.
The Marlins television broadcast team of Rich Waltz and Tommy Hutton are back on FOX Sports Florida.
The Spanish TV team of Raul Striker Jr. and Cookie Rojas also returns.
And on Spanish-language radio, Rafael "Felo" Ramirez, the 2001 Frick Award winner, and Luis "Yiky" Quintana return.
Joe Frisaro is a reporter for MLB.com. He writes a blog, called The Fish Pond. Follow him on Twitter