The Marlins' first baseman played a big role in Miami's 6-4 win over the Reds on Saturday night.
Lee belted a two-run homer and had three RBIs. The homer was his ninth of the season, and first at Marlins Park.
As of Friday night, it was unclear if Lee would be ready to play.
The veteran first baseman exited Friday's game due to a sore neck. The ailment occurred when he was tagged out after sliding headfirst into second base.
"I'm fine," Lee said. "I saw the doctor [on Friday night]. The doctor said that [this type of neck injury] is very common in football. All I experienced was the numbness in my fingers, that's why I came out."
After Friday's game, Lee told manager Ozzie Guillen that he would be ready to play.
"When I left here, I was getting the feeling back in my hand," Lee said. "I told the trainer, 'I'm not day to day. I'll be ready tomorrow.'"