Ruggiano has dealt with back spasms and the tight oblique for a few days. He said it bothered him during an at-bat against Jonathan Papelbon in the ninth inning of Tuesday's 1-0 loss.
The Marlins plan on giving Ruggiano a day or two of rest, and they hope that he will be fine for their four-game series that starts Thursday night in Colorado.
"It's probably a combination of stiff back and, I don't know, changing my swing a little bit," Ruggiano said. "I felt it a couple of days ago. It's just something I've been trying to get through.
"I honestly think, I will need a day or two, hopefully. I'm getting an opportunity and I want to play. I also don't want to be out there and hinder the team. I want to make sure when I'm out there, I'm able to swing 100 percent."
Ruggiano added that he didn't approach manager Ozzie Guillen about being in discomfort.
"I think he could tell," the outfielder said. "I think they've been around the game long enough, they can kind of see. I said something last night to the trainers that I felt it, specifically on the Papelbon at-bat. They could tell today."
Ruggiano felt something grab when he struck out against Philadelphia's Roy Halladay in the third inning. In the fourth, Gorkys Hernandez replaced Ruggiano in center field.
The Marlins are planning to monitor Ruggiano on a daily basis. The outfielder has been one of their most productive hitters, batting .326 with 10 home runs and 26 RBIs.
He had two at-bats against Halladay, striking out both times.
The Marlins are dealing with several injuries of late. Infielder Nick Green has a sprained left thumb. Although he isn't expected to go on the DL, he hasn't been available.
On Wednesday, Bonifacio, on the DL with a sprained left thumb, began his rehab assignment for Class A Jupiter. He is planning on being in the Marlins' lineup on Sunday in Colorado.