Collins' appeal to the league was to call the hit an error on Wright. But after reviewing the play, MLB said Upton's single stood.
Would Guillen seek an overturn to help his pitcher throw a no-hitter, even if it meant an error was charged to his infielder?
"Of course I would," the Marlins manager said. "I try to protect my players. I will do everything in my power to protect my player. Yes, I think he did a good job. Now, it's a league decision, yes or no."
Guillen added that no-hitters are seemingly routine.
The same night as Dickey threw a one-hitter, Matt Cain of the Giants tossed a perfect game. There have been five no-hitters this year, including two perfect games.
And there have been three no-hitters since June 1.
The Marlins were limited to one hit in their 11-0 loss to the Rays on Friday.
"Before, no-hitters were like, 'Wow!' Now, they come every other day. Everybody is throwing no-hitters," Guillen said.
The Marlins rotation features three starters who have tossed no-hitters in their careers -- Anibal Sanchez, Carlos Zambrano and Mark Buehrle.
Buehrle has a no-hitter and perfect game to his credit.
Guillen managed both of those games when Buehrle was with the White Sox.
"Buehrle threw a perfect game," Guillen said. "If that was the '60s, when you throw a no-hitter, people were like, 'Wow, look at this guy.' Now you see in the paper every other day somebody throws a no-hitter. That doesn't impress me. Don't get me wrong, no-hitter is a no-hitter. That's one of the best ego and great things that can happen for a pitcher."