Before Friday's game against the Rays at Tropicana Field, Ramirez was plunked in the nose by a ball during batting practice.
He was taking flips in the cages, and the ball deflected off a screen and clipped him in the face.
Ramirez was given Friday off, but at the hotel after the game, the third baseman told manager Ozzie Guillen that he could play on Saturday.
There is some swelling in the nose, but Ramirez says he has no concussion symptoms.
"Just a little bit of a headache," Ramirez said. "The only thing they say is if I get hit again, I'm going to need emergency surgery. I'm trying to go out there and play and hope nothing happens. If something happens, it's going to be worse. If something happens, I might be out for the whole season."
Ramirez has to guard against bad hops and being hit in the face area while running the bases.
"He's back, that's good news," Guillen said. "He has a broken nose. We appreciate as a team and as his manager that he will be out there. Not many people with that problem will go out and perform. They might take two or three days to see how they feel. He says he feels better today, and that's why he is playing."
Ramirez is batting .259 with 11 home runs and 37 RBIs.
"It's not a huge thing, but a broken bone is a broken bone," Guillen said. "It's going to take a little time to heal. But in the meantime, he's playing."