Cishek, who grew up in Falmouth, Mass., was a huge Red Sox fan growing up.
"Obviously it's a little different, because it's the team you grew up watching your entire life," the 25-year-old right-hander said, "but out there, it wasn't any different."
One of the promising young relievers in the National League, Cishek allowed one hit while registering a strikeout in the eighth inning against Boston in Miami's 4-1 win at Marlins Park.
Cishek openly roots for New England teams. During the Miami Heat playoff series with the Boston Celtics, Cishek attended one game at the AmericanAirlines Arena wearing a Ray Allen jersey.
As a kid, Cishek's favorite player was Nomar Garciaparra. He also was a fan of Derek Lowe and Bronson Arroyo.
"I was a pretty solid fan," Cishek said. "All the New England sports, my family cheered for them. I loved the Red Sox growing up as a kid. Nomar was my favorite player."
Early in the season, Cishek met and got an autograph from Garciaparra, now an ESPN analyst.
When the Marlins faced the Reds in Cincinnati in April, Cishek met Arroyo.
Cishek is a rising talent in Miami's bullpen. The right-hander with the sidearm delivery is 4-0 with a 2.03 ERA, striking out 27 in 26 2/3 innings.
On Monday, Cishek worked around a two-out single by retiring Dustin Pedroia on a grounder to third.
"Once the game went on, it was fine," Cishek said. "I wasn't even thinking about [facing Boston] when I was pitching."