Infante's grandfather passed away on Sunday.
The second baseman heard the news before the team faced the Indians, and he immediately made plans to return to Venezuela for the funeral.
Donnie Murphy, who started in Infante's place on Sunday at Cleveland, was back in the lineup at second on Monday in the series opener with the Rockies at Marlins Park.
"He should be back [Tuesday]," Guillen said. "You never know what is going to happen from one day to another in Venezuela. Plane may be late. I'm not counting on him for three or four days. He's not in my mind right now. I've got to wait and see when he gets here."
Infante is having an All-Star caliber season, batting .326 with six home runs and 20 RBIs.