Guillen also wouldn't change the plan he used in Tuesday night's 2-1 loss to the Mets if he had to do it all over again.
The most controversial inning of Guillen's tenure as Marlins manager came in the seventh.
Guillen lifted Josh Johnson after he walked Lucas Duda with two outs. It was the beginning of a stretch of four different pitchers walking four straight batters. Randy Choate, Steve Cishek and Mike Dunn also issued walks, forcing in the tying run.
"People can second guess after the fact, that's easy," Guillen said. "We had a plan. I told JJ on the mound, 'We've got a plan. We're going to stick with the plan. If we fail, that's on the mound.' "
Johnson was brilliant in 6 2/3 innings, throwing 102 pitches. But pitch count wasn't the issue.
"If something happens, I can sleep," Guillen said. "If somebody would have told me to not do it because we're going to walk four guys, then of course not. The pitching matchups we had, that's what we wanted. It didn't work for us because we were walking people."
Guillen says he likely won't use his starters for more than 110-115 pitches.
"They can second-guess me, I've been second-guessed all of my life," the Miami manager said. "But as long as I can sleep, and I know what I'm doing, and I believe in what my coaching staff is doing out there, that's fine with me."