The biggest change is Guillen dropped Giancarlo Stanton from cleanup to sixth, and inserted Logan Morrison into the No. 4 spot. Stanton entered Tuesday 2-for-10 in the homestand, compared to Morrison's 5-for-9.
The move also puts a left-handed bat behind Hanley Ramirez, who bats third.
"I moved Stanton a little bit to make him relax a little bit, and to take advantage of the way LoMo is swinging the bat right now," Guillen said. "LoMo gives some lefty protection to Ramirez, and that's the reason we did it.
"Hopefully, pretty soon, we'll move those guys back to where they should be."
With Guillen, performance will dictate where players hit in the lineup.
"If I don't like the way you play, I bench you," the manager said. "I have to take more advantage of the production from one to another. I like the way LoMo is swinging the bat right now."